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Do not use vitamin b12 injection for dogs if it appears cloudy or color has been changed or vial is leaked or damaged, these are the signs of expiration

Clin Chem 2011;57:1436-43

Green et al 26 Severe clinical abnormalities should be treated intensively with B 12 , cyanoB 12 or hydroxyB 12 : HydroxyB 12 is commonly used in Europe, often at intervals of 23 months, as it seems to have better retention than cyanoB 12

If intramuscular administration is suspected, the washout periods for the intramuscular route should be observed

Scientists observed that as organisms age or gain excess weight, their fat cells (adipocytes) produce excessive amounts of NNMT